STEM CELL
BIOLOGY AND REGENERATIVE MEDICINE
Pathology/Dev
Bio 296 Winter Quarter 2009-2010
Room M??TBD M F 1:15-3:05
Course
Directors: Renee Reijo Pera, Minx Fuller, Michael Longaker,
Roel Nusse and
Irv Weissman
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A-side,
Basic Science
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B-side,
Medical
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Week
1
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Monday ¼ |
Stem Cell concepts Roel Nusse |
Regenerative
medicine: Challenges in the clinic, Promises from the lab Mike Longaker |
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WED |
Discussion Sections? |
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Friday 1/8 |
Stem Cell Methods Roel Nusse |
Imaging Stem cells Joe Wu?? |
Week
2
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Monday 1/11 |
Hematopoiesis
as a paradigm for adult or tissue stem cell biology Irv Weissman |
Tools for molecular analysis of stem cells Steve Quake |
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WED |
Discussion Sections? |
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Friday 1/15 |
Origin and regulation of normal and leukemic hematopoietic stem cells Irv Weissman |
HSC transplantation Judith
Shizuru |
Week
3
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Monday 1/18 |
Dr. Martin Luther King, Jr. Day – NO LECTURES |
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WED |
Discussion Sections? |
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Friday 1/22 |
Cell cycle control and the regulation of proliferation vs quiescence in stem cells and their lineages Julien Sage |
Oncogenes and Stem Cells Mike Cleary |
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Week 4 |
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Monday 1/25 |
Stem cells and the niche: Asymmetric Division Margaret Fuller |
Artificial niches in stem cell culture and
therapeutic transplantation Kevin Healy, UC Berkeley |
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WED |
Discussion Sections? |
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Friday 1/29 |
Stem cells in epithelia: Intestine, colon, and mammary gland Roel Nusse
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Breast
Cancer Stem Cells Mike Clarke |
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Week 5 |
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Monday 2/1 |
Epithelial
stem cells: Skin, hair and wound repair
Tony Oro |
Skin regeneration & skin
tumors Paul Khavari |
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WED |
Discussion Sections? |
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Friday
2/5 |
Neuroblasts
and neural precursors in early brain development Ricardo
Dolmetsch |
Regenerating spinal cord Nobuko Uchida, Stem Cells, Inc. |
Week
6
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Monday 2/8 |
Neural stem cells and Adult Neurogen-esis/ Cancer Therapies and the brain Theo Palmer |
Brain Cancer: Childhood medulloblastoma Mike Edwards |
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WED |
Discussion Sections? |
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Friday 2/12 |
Stem cells in reserve: Muscle satellite cells and regulation of muscle repair Tom Rando
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Muscular
Dystrophies: The promise of stem cell therapy
Tom Rando |
Week
7
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Monday 2/15 |
PresidentsÕ Day – NO LECTURES |
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WED |
Discussion Sections? |
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Friday 2/19 |
Early developmental decisions in mammals: Origin of ICM and germline Renee Reijo Pera |
Gastrulation Jeremy
Reiter UCSF?
Or Renee? |
Week
8
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Monday 2/22 |
ES Cells: Transcriptional Regulation of Pluripotency Margaret Fuller |
Teratocarcinoma Mike Clarke |
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WED.2/25 |
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Friday 2/26 M114 |
Epigenetic maintenance of cell state Joanna Wysocka |
Reproductive
technology Barry Behr |
Week 9 |
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Monday 3/1 |
Aging and Stem Cells Anne Brunet |
Dedifferentiation and regeneration in limbs Helen
Blau |
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WED |
Discussion Sections? |
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Friday 3/5 |
ICM/ES to Endoderm Eric
Chiao |
Strategies
for replacement therapy for type 1 diabetes Magali Fontaine |
Week 10 (Dead Week) |
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Monday 3/8 |
Aging
and Stem Cells Howard Chang |
ÒCan stem cells make the deaf hear and the blind see?Ó Stefan
Heller |
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WED |
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Friday 3/12 |
Reprogramming Marius Wernig |
ES cells, cardiac stem
cells, and heart repair Deepak Srivastava, UCSF |
Week 11 (End-Quarter Examinations) No Lectures |
NB. GRAD ADMISSIONS –Mar ??
Make it all parts required for everyone. 3-5 credits for all