Marius Wernig Laboratory
“Only those who attempt the absurd can achieve the impossible.”
--Albert Einstein
 |
|
|
Research in the Wernig Lab
Our lab is interested in two major areas of stem cell biology. One focus is the epigenetic reprogramming of somatic cells into pluripotent stem cells and this technique's translational applications for regenerative medicine. Another area of interest is the study of self-renewal mechanisms of mammalian neural progenitor cells, with the hope of identifying novel approaches to better understand brain cancer.
Selected Publications
Wernig M, Lengner CJ, Hanna J, Lodato MA, Steine E, Foreman R, Staerk J, Markoulaki S, Jaenisch R "A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types." Nat Biotechnol 2008; 26: 8: 916-24 More » Wernig M, Zhao JP, Pruszak J, Hedlund E, Fu D, Soldner F, Broccoli V, Constantine-Paton M, Isacson O, Jaenisch R "Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease." Proc Natl Acad Sci U S A 2008; 105: 15: 5856-61 More » Wernig M, Meissner A, Foreman R, Brambrink T, Ku M, Hochedlinger K, Bernstein BE, Jaenisch R "In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state." Nature 2007; 448: 7151: 318-24 More » |
Lab Info
What's new
|
